COND: -1, (Dazed until next turn), (Fatigued next turn)
The flicker of motion drew Roy's attention, giving him the opportunity to shield his eyes, but he still took the hit from Ninja 21. So he was the clear threat, noted. His hand, already prepared with brass fistloads, smashed into Ninja's kidneys, before moving to set a lock on the Ninja.
But with his pistol hand free, Roy had no qualm about 'overkill.' Restraint in this case, meant he shot Ninja's leg, not his head.
Fortitude: 1d20+7 25
Toughness: 1d20+4 22
Brass Knuckles [PA -2/+2]: 1d20+9 20
That should be Toughness DC 20, and initiating Fast Grab.
Not sure how we officially handle grabs, but as a note, Improved Hold and Improved Grab...
Surge and use...
Silenced Machine Pistol: 1d20+10 22
Toughness DC 18 + Multiattack.