Bullseye never misses.
Daredevil can dodge Bullseye's attacks.
Assuming they're both PL 10, what would Daredevil's Defense be? Well, he's a phenomenally skilled combatant, so let's give him a BDB of +9. Additionally, he's almost ridiculously dexterous, so let's say Dex 20 with a Super-Dex of +5. This puts his total Defense at 29, before applying feats. With Feats, he could manage a 36 vs. a single opponent.
Now then, Bullseye never misses. We give him a BAB of +10 and a Dex of 20. Now we add Attack Focus, Point Blank Shot, and All-Out Attack. Bullseye maxes out at +22 on an attack within 30 ft. He needs to roll a 14 to hit Daredevil. Not bad. Not easy, but doable. Assuming Daredevil does anything other than full Expertise on his round, Bullseye's chances just keep getting better. If Daredevil is in any way distracted for even a moment, Bullseye nails him effortlessly.
Even assuming a truly maxed out defender (Defense 35 before feats are applied), keep in mind that all of this is dependent on a Dodge bonus that can be taken away. Even with maxed Combat Sense, the highest a flat-footed PL10 character can manage is 30. There are ways for characters to score telling hits, even without an Accuracy power.
Please note that Bullseye never misses. At PL10, he can nail a 26 Defense any time he wants (if he rolls below 10, he just spends a Villain Point. He hits a 27 within 30'. With All-Out attack, he hits a 32). Anyone with higher defenses than that deserve a frigging chance, especially since a high defense is probably the only thing they've got going on. An Accuracy power bumps his effortless shot to 36 (37 within 30'). Oh, by the way, with All-Out Attack, he's swinging with 41/42. If he also flew, he could get that to 43. If under the instruction of a Leadership-wielding teammate, we're looking at 44 Defense hit effortlessly. Oh wait, we can always use extra effort on the power (it ain't permanent, is it?) to get up to 46. Are you scared yet? Even if this power only affects one type of attack, it completely dismantles the benefits of a high Defense. Oh, and anyone without a gigantic Defense is looking at a Power Attack every round, along with Rapid Shot (or Strike) and maybe Heroic Surge or Multi/Autofire.
"Okay, -5 from Power Attack and -8 from the combination of Rapid Shot and Autofire. The guy's Defense is 20, you're his Dodge buddy, and he's behind 9/10ths cover. His total Defense is 29."
"I roll an 8, a 7, a 10, and an 11. Let's see, +36 minus 13 is 23. I roll a 30 as my lowest attack. He can save vs. +16L four times. What? He's only stunned? I use a Heroic Surge with Surprise Strike to do it one more time. I roll a 4. Since he's stunned, that hits handily. He can save vs. 21L."
And this is every round almost every fight. No thought, no strategy, no need for tactics. Every villain this character ever fights needs either maxed out Defense (making them too hard for the rest of the party to hit) or so much Damage Save that they can survive 4 +16L hits every round (making them too tough for the rest of the party to hurt).
Shall I continue? Do you see the problem yet?
Of course, your mileage may vary, and all that.
It's not the side-effects of the cocaine
I'm thinking that it must be love . . .